Biology · Biotechniques
According to the 'proton sponge hypothesis' associated with chemical gene delivery using poly(ethylenimine) (PEI)/DNA complexes, what is the correct chronological sequence of events following endocytosis? (A) PEI/DNA complexes are internalized via endocytosis. (B) Endosomal V-ATPases pump protons continuously into the vesicular interior. (C) Influx of water and chloride ions occurs to balance the osmotic gradient. (D) The vesicle swells due to the entry of ions and water, leading to endosomal rupture.
Verified Solution4 OptionsUpdated: October 2026👁️1 View
Share:
- 1(B), (C) and (D) only
- 2(A), (B), (C) and (D)✓
- 3(A), (B) and (C) only
- 4(A), (B) and (D) only
Correct answer
(A), (B), (C) and (D)
Download Single Question PDF
Save this question and verified answer as a clean study sheet with live clickable link.
👥
Share with Friends & Study Groups
Challenge your peer aspirants on WhatsApp or Telegram to solve this question!
Online Test Series
Start Free Mock Test →Preparing for Biology?
Practice full-length mock tests with real exam timers, instant score analysis, and all-India ranking.
Chapter Practice
Practice Biotechniques MCQs →Want more practice questions on Biotechniques?
Solve complete topic-wise tests with detailed solutions on GkGet.
Related Practice Questions
Recommended practice questions in Biology · Biotechniques