Biology · Cell Biology
A protein found in the Golgi compartment was found to be degraded rapidly at mitosis. Golgi extracts (isolated from G1 and M phase cells treated with deubiquitination inhibitors) were treated with glycosidase and western blots done using antibodies against the protein. The western blot shows that the protein is shifted to a lower molecular weight upon glycosidase treatment in both G1 and M phases, and a high-molecular-weight smear (indicative of ubiquitination) is observed only in the M-phase sample. Identify the statement that CANNOT be made based on the data.
Verified Solution4 OptionsUpdated: October 2026👁️1 View
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- 1The protein is not ubiquitinated in G1.
- 2The protein is ubiquitinated but not glycosylated in M-phase.✓
- 3The protein is glycosylated and ubiquitinated in M-phase.
- 4The protein is glycosylated in G1 and M-phase.
Correct answer
The protein is ubiquitinated but not glycosylated in M-phase.
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