Biology · Genetics
A protein-coding gene in mice was mutated such that the resultant protein was non-functional. The phenotypic effect of this mutation was observed in homozygous mutant mice, in heterozygous mice that inherited the mutation from the mother, and in heterozygous mice that inherited the mutation from the father. This suggests that:
- 1The gene is X-linked
- 2The gene possibly has more than two alleles
- 3The mutation acts as a dominant negative✓
- 4The gene is imprinted
Correct answer
The mutation acts as a dominant negative
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