A patient with SCID (Severe Combined Immunodeficiency) due to ADA deficiency undergoes gene therapy. A retroviral vector is used to deliver the functional ADA gene into the patient's lymphocytes. Which of the following statements regarding this process is correct?

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Science · Gene Therapy

Verified Solution4 OptionsUpdated: October 2026👁️1 View

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Retroviral vectors integrate into the host genome ensuring long-term expression.

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Answer 1

Retroviral vectors cannot infect mammalian cells under any conditions.

Answer 2

Gene therapy in SCID is completely ineffective due to immediate immune rejection.

Answer 3

ADA deficiency can be corrected by enzyme replacement therapy only.

Answer 4

Retroviral vectors integrate into the host genome ensuring long-term expression.

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