Biology · Pharmacology

A patient with acute renal failure (ARF) and oliguria is administered low-dose dopamine. What is the expected physiological mechanism and therapeutic drug effect?

Verified Solution4 OptionsUpdated: October 2026👁️1 View

1Severe systemic hypotension and profound bradycardia due to central baroreceptor reflex activation
2Increased renal blood flow, urine output, and glomerular filtration rate (GFR) via dopaminergic receptor stimulation✓
3Decreased cardiac contractility and heart rate via selective β2 block
4Systemic vasoconstriction and increased systemic blood pressure via α1 receptor stimulation

Correct answer

Increased renal blood flow, urine output, and glomerular filtration rate (GFR) via dopaminergic receptor stimulation

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