Medical Science · Hematological Procedures and Care
A patient is scheduled for a bone marrow biopsy and aspiration to evaluate unexplained anemia. Which option correctly integrates the type of procedure, preferred site and position, contraindication, and most common complication?
- 1Tibia is the most preferred site in adults; lateral position is contraindicated; DIC is a relative contraindication.
- 2Trephine biopsy removes a 1-2 cm bone core using a Jamshidi needle; PSIS is the preferred site in adults with prone/lateral position; sternum is avoided in young children due to risk of mediastinal puncture.✓
- 3Bone marrow aspiration removes a bone core; PSIS is avoided in adults; thrombocytopenia is an absolute contraindication.
- 4Trephine biopsy removes only fluid; sternum is preferred in all ages; prone position is mandatory; bleeding is the most common complication.
Correct answer
Trephine biopsy removes a 1-2 cm bone core using a Jamshidi needle; PSIS is the preferred site in adults with prone/lateral position; sternum is avoided in young children due to risk of mediastinal puncture.
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