Biology · Cell Biology
A mutation disrupts the mannose-6-phosphate tagging of proteins. Which of the following cellular consequences is MOST likely to occur?
- 1Accumulation of proteins in the ER lumen
- 2Failure of lysosomal enzyme targeting✓
- 3Defective mitochondrial protein import
- 4Blockage of nuclear pore transport
Correct answer
Failure of lysosomal enzyme targeting
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