Biology · Cell Biology and Biomolecules
A cell population survives sudden temperature shifts from 5°C to 42°C without losing membrane integrity. Lipid analysis shows a high cholesterol-to-phospholipid ratio. Which mechanistic explanation best accounts for this survival?
Verified Solution4 OptionsUpdated: October 2026👁️1 View
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- 1Cholesterol uniformly increases membrane fluidity at all temperatures by disrupting fatty acid packing
- 2Cholesterol restricts phospholipid movement at high temperatures and prevents excessive ordering/rigidity at low temperatures, acting as a fluidity buffer✓
- 3Cholesterol converts the lipid bilayer into a micellar structure, preventing phase transitions
- 4Cholesterol completely replaces phospholipids to form a rigid monolayer membrane
Correct answer
Cholesterol restricts phospholipid movement at high temperatures and prevents excessive ordering/rigidity at low temperatures, acting as a fluidity buffer
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