Biology · Human Physiology and Digestive System
A 34-year-old male develops abdominal distension, excessive gas formation, and watery diarrhea after consuming milk products. A hydrogen breath test is positive after lactose ingestion. Which sequence BEST explains the pathophysiology of his condition?
- 1Lactase deficiency → lactose reaches colon → bacterial fermentation → hydrogen gas production and osmotic diarrhea✓
- 2Bile salt deficiency → impaired fat digestion → osmotic diarrhea
- 3Pancreatic enzyme deficiency → fat malabsorption → steatorrhea → diarrhea
- 4Lactase deficiency → glucose malabsorption → colonic bacterial fermentation → gas and osmotic diarrhea
Correct answer
Lactase deficiency → lactose reaches colon → bacterial fermentation → hydrogen gas production and osmotic diarrhea
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