A 19-year-old female diagnosed with schizophrenia develops a high fever, altered mental status, and marked muscle rigidity three days after starting fluphenazine. What is the most appropriate immediate management for this life-threatening condition?

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Science · Adverse Drug Reactions

Verified Solution4 OptionsUpdated: October 2026👁️1 View

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Correct answer

Discontinue fluphenazine and administer intravenous dantrolene.

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Answer 1

Continue fluphenazine and add an anticholinergic drug like benztropine.

Answer 2

Discontinue fluphenazine and substitute with haloperidol.

Answer 3

Discontinue fluphenazine and administer intravenous dantrolene.

Answer 4

Continue fluphenazine and add oral diazepam.

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