Biology · Biochemistry
Why does the presence of a proline residue destabilize an α-helix? A. Proline introduces a destabilizing kink in the α-helix. B. In proline, the nitrogen atom is part of a rigid ring, restricting N-Cα bond rotation. C. The peptide bond nitrogen of proline has no substituent hydrogen to participate in hydrogen bonding. D. Proline works explicitly as a universal helix linker. Choose the correct combination:
- 1B, C and D only
- 2A, B, C and D
- 3A, B and C only✓
- 4A, B and D only
Correct answer
A, B and C only
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