Biology · Molecular Biology & Therapeutics
How did Karikó and Weissman test their hypothesis regarding the immune recognition of in vitro transcribed RNA?
Verified Solution4 OptionsUpdated: October 2026👁️1 View
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- 1By altering the genetic code of the dendritic cells to inhibit all pattern recognition receptors
- 2By producing different variants of mRNA, each with unique chemical base alterations, and delivering them to cells✓
- 3By co-administering synthetic mRNA alongside high-dose anti-inflammatory immunosuppressants
- 4By completely eliminating the uracil content using artificial synthetic base substitutes
Correct answer
By producing different variants of mRNA, each with unique chemical base alterations, and delivering them to cells
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